Analysis of Postmortem Brain Tissue from the Autism BrainNet Collection — Request for Applications

Grants awarded through this request for applications (RFA) were intended to advance the understanding of autism spectrum disorder through analyses of human postmortem brain tissue donated to the Autism BrainNet collection. Through this RFA, the Simons Foundation Autism Research Initiative (SFARI) encouraged individual and collaborative applications that study and compare gene expression at the tissue and single-cell level. Such analyses could also have included alternative splicing/isoform analysis, RNA editing, noncoding RNAs, epigenetic modifications and/or proteomics. Studies of cellular neuroanatomy and immunohistochemical research on identified transmitter systems were also welcomed. The program aimed to leverage the Autism BrainNet postmortem brain tissue repository to generate new insights into the molecular and cellular basis of autism.