BRAIN Initiative: Production and distribution facilities for brain cell type-specific access reagents (U24 Clinical Trial Not Allowed)

This BRAIN Initiative Notice of Funding Opportunity (NOFO) supports scaled reagent production and distribution facilities involving technologies to access brain cell types. The program encourages facilities for production and distribution of these reagents by a broad set of neuroscientists. This NOFO is part of the BRAIN Initiative Armamentarium for Brain Cell Access transformative project. Efforts will be supported to produce and distribute gene transfer, gene regulation, and genome engineering reagents for use in both genetically tractable and less tractable systems, including primates and human tissue, which are relevant for future translational efforts. Reagents to be produced and distributed are those designed and validated under other NOFOs from the Armamentarium transformative project. This funding opportunity uses the U24 cooperative agreement mechanism, which involves substantial NIH scientific and/or programmatic involvement with the awardee during performance of the funded project.