Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01 Clinical Trial Not Allowed)

The goal of this NOFO is to support applications for novel theory and methods development that enable better understanding of how genetic and non-genetic factors contribute to complex trait variation across individuals, families, and populations. Approaches should be interdisciplinary drawing from the natural and social sciences, account for interdependencies across scales of biological, social, and ecological organization, and make extensive use of theory, modeling, and validation with available large-scale datasets. This R01 grant from the National Institutes of Health supports research that advances the understanding of genetic architecture and complex human traits through innovative theoretical and methodological approaches. The funding mechanism is designed to promote interdisciplinary collaboration that integrates multiple levels of biological, social, and ecological analysis.