Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R01 Clinical Trial Optional)

About this opportunity

This Notice of Funding Opportunity (NOFO) invites research grant applications that propose the development and evaluation of novel radioligands for positron emission tomography (PET) or single photon emission computed tomography (SPECT) imaging in human brain and the incorporation of, pilot or clinical feasibility evaluation from previously collected data in pre-clinical studies. These studies are expected to provide the requisite data needed to advance promising PET ligands for use in clinical research. The program supports the development of innovative imaging biomarkers that can be used for drug discovery and for understanding the pathophysiology of central nervous system (CNS) disorders. Funded projects will contribute to advancing neuroimaging technologies that enable better diagnosis, treatment monitoring, and understanding of brain disorders.

research positron emission tomography PET imaging SPECT imaging radioligands central nervous system CNS disorders drug discovery pathophysiology neuroimaging biomarkers

Who can apply

Applicant Types

organization

Organization Types

nonprofit, for profit, academic, government, tribal

Project Locations

🇺🇸 United States

Region

United States

How to apply

Institutional approval

Stages

1 single_stage

Required documents

research_proposal · budget

Post-award obligations

final_report
acknowledge_funder

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External Application

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