Developmental pathway funding scheme: invited stage two

The Developmental Pathway Funding Scheme (DPFS) stage two provides funding to develop and test novel therapeutics, medical devices, diagnostics and other interventions. This funding opportunity is open to invited applicants only who have successfully completed stage one applications. Projects can start and finish at any stage on the developmental pathway from early development, through pre-clinical refinement and testing to early-phase clinical studies and trials (up to phase 2a). The scheme supports academically-led translational projects that aim to improve prevention, diagnosis, prognosis or treatment of significant health needs, or develop research tools that increase the efficiency of developing interventions. All human diseases and medical interventions are eligible for support, both in the context of UK healthcare and addressing global health issues. The program typically funds projects with two to four milestones including specific success criteria that reflect major progress points and allow decision-making on project progression.