Investigator Initiated Clinical Trials

The Novo Nordisk Foundation provides grants to strengthen opportunities for conducting larger clinical trials in Denmark without commercial purpose. The ultimate objective is to improve patient treatment through new medicine and technology and ensure the highest quality in treatment. Grants support both monocentric and multicenter national trials. For multicenter international clinical trials, the coordinating investigator and trial must be anchored at a Danish hospital. Clinical trials must conform to good clinical practice guidelines (GCP), demonstrate clinical relevance and scientific quality, and include detailed protocols with power calculations, data management plans, and statistical analysis plans. Randomized controlled trials are preferred, though nonrandomized trials are also accepted. All funded trials must be registered at ClinicalTrials.gov or the Clinical Trials Information System (CTIS), and anonymized data must be made publicly available upon completion.