Life Sciences Transformational R&D Investment Fund (TRIF) Pilot

Department for Science, Innovation and Technology (DSIT), UK Government
Award GBP 10M–25M
Closing date 715 days left · Mar 31, 2028
Location Global
For Orgs

About this opportunity

The Life Sciences Transformational R&D Investment Fund Pilot offers capital grants to support large-scale R&D projects in the UK life sciences sector. This newly established £50 million fund aims to boost research and development within the UK's Life Sciences sector by supporting large-scale investments focused on innovation and strengthening health resilience. Projects must exceed £100 million in total costs to be eligible. The fund prioritises projects with the potential to generate economic benefits, including substantial contributions to Gross Value Added (GVA), creation of high-wage, high-skilled jobs, and generating R&D spillover benefits. This fund complements the separate Life Sciences Innovative Manufacturing Fund (LSIMF) and supports projects in human medicines, medical diagnostics, and MedTech products. The grant is set at the minimum level necessary to ensure projects proceed while adhering to UK subsidy regulations, typically ranging from 10-20% of total project costs.
Monthly panel reviews starting October 2025
innovation life sciences pharmaceuticals human medicines medical diagnostics MedTech medical devices active pharmaceutical ingredients drug development health resilience clinical trials

Who can apply

Applicant Types

organization

Organization Types

for profit

Project Locations

🇬🇧 United Kingdom

Region

United Kingdom

How to apply

Interview required Matching funds

Stages

  1. 1 multi_round

Required documents

budget · research_proposal

Review process

Three-stage process: (1) Application Form 1 - Expression of Interest evaluated for eligibility and alignment with fund objectives; (2) Objective 1 assessment includes panel interview with independent experts evaluating innovation, health resilience benefits, project viability and deliverability; (3) Objective 2 includes Application Form 2 with detailed financial and economic information, followed by due diligence assessment for value for money, subsidy control compliance, and project deliverability.

Restrictions

  • reporting_requirements
  • geographic_restrictions

Post-award obligations

  • remain_in_field