NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)

The NIH Exploratory/Developmental Grant (R21) supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. This funding opportunity is designed to encourage new exploratory and developmental research projects that have the potential for high impact in biomedical and behavioral research. The R21 grant mechanism is intended for projects that are in their early stages and may be untested but offer potentially transformative results. This parent announcement allows for broad application across multiple research areas under NIH, excluding clinical trials.