NIH Research Project Grant (Parent R01 Clinical Trial Required)

The NIH Research Project Grant (R01) supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s). This Parent Notice of Funding Opportunity Announcement requires that at least one clinical trial be proposed. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions. This funding opportunity covers a broad range of health research areas including cardiovascular diseases, diabetes, mental health, aging, infectious diseases, neurosciences, and many other biomedical research fields. The R01 is the original and historically oldest grant mechanism used by NIH, and it is designed to support discrete, specified research projects with clearly defined objectives and methodologies.