PhD Scholarship in Cryopreservation

This PhD scholarship focuses on optimising cryopreservation protocols for specific reproductive cells by tailoring a number of variables. Cryopreservation of cells involves storage at very cold temperatures to minimise biochemical activity and prevent damage to the cells. However, the freezing process is damaging and requires cryoprotectants and tailored freezing protocols to enable cell survival. The project will involve developing novel cryopreservation protocols for reproductive cells and testing the outcomes on embryos, sperm, and oocytes. Techniques will include in-vitro fertilisation, toxicity assays, microscopy and embryonic manipulation and observation. This project has significant potential benefits for assisted reproductive technologies for both humans and livestock, where post-cryopreservation success remains low with time, financial, and emotional costs. The project has strong industry connections and is ideally suited for students interested in cross-disciplinary research.