Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of NIDDK (R21 Clinical Trial Not Allowed)

This Notice of Funding Opportunity invites applications for innovative basic and translational pilot research projects within the mission of the NIDDK that are aligned with NIH HIV/AIDS research priorities. The program supports research addressing multiple overarching priorities including elucidation of unique pathophysiological mechanisms contributing to HIV comorbidities, coinfections, and complications affecting organs, tissues, and processes within the mission of the NIDDK. The opportunity also supports interrogations into biological mechanisms underlying HIV reservoirs in NIDDK-relevant tissues, which are important for developing strategies for long-term viral suppression or eradication. Additionally, the program addresses health-impeding social determinants of health that may affect complications or viral reservoirs within NIDDK's mission through multiple pathways.