Collaborate with the functional genomics screening laboratory

UK Research and Innovation (UKRI) - Medical Research Council (MRC) Original Source

About This Opportunity

Apply to collaborate with the functional genomics screening laboratory (FGSL) on projects using complex human in vitro models for CRISPR screening to better understand model biology and enable target identification. The FGSL is a joint venture between MRC, AstraZeneca and the Milner Therapeutics Institute, University of Cambridge. It has been set up to enable UK based academic groups and where space allows UK based small medium enterprises and industry to have access to a state-of-the-art arrayed functional genomics screening laboratory. Screens will be carried out by scientists employed at Milner Therapeutics Institute (MTI), with all screens run as collaborations to ensure the best possible outcome and data. Applicants define the purpose of the screen and desired outcomes, providing the in vitro model, while the FGSL team conducts the screening work. Financial support for screens (consumables) is available either from AstraZeneca or from a screening access fund provided by MRC.

Applications reviewed twice a year in May/June and November/December

Who Can Apply

Region
United Kingdom
Residency
United Kingdom
Project in
United Kingdom
Applicants
individual, team, organization
Organizations
academic, for profit

Application Details

Stages

  1. 1 rolling

Required documents

research_proposal

Review process

Applications are reviewed by the Joint Steering Committee (JSC) comprising two representatives each from MRC, AstraZeneca, and Milner Therapeutics Institute, chaired by the MRC Director of the Functional Genomics Initiative. Assessment areas include in vivo recapitulation and translatability of biological model, availability and scalability of the cell model, feasibility of assay endpoint for screening, assay controls available, and gene editing feasibility of the cell model.

Additional benefits

  • equipment
  • training

Restrictions

  • reporting_requirements

Post-award obligations

  • share_data