Experimental Medicine Stage One Grant

The Medical Research Council (MRC) offers funding for experimental medicine research to investigate the causes, progression and treatment of human disease. Applications must include an experimental intervention or challenge in humans with established safety profiles, designed to validate a mechanistic hypothesis. The project should be based around a clearly articulated gap in understanding of human pathophysiology and have a clear path to clinical impact. Successful projects will generate new mechanistic insights that may identify opportunities to modify disease pathways or enable the future development of novel therapeutic or diagnostic approaches. This is an ongoing funding opportunity with application rounds closing every April and October. There is no limit to the amount of funding applicants can request or the length of the project, with MRC funding 80% of the project's full economic cost.