NHMRC project "Engineered drugs that specifically inhibit clotting"

This PhD project is part of a large NHMRC-funded initiative aiming to develop engineered drugs that specifically inhibit clotting in specific sites, and eliminating the risk of major bleeding complications associated with conventional anticoagulant therapies. The project utilizes fluid mechanics, microfluidics and machine learning to develop rapid testing methods for novel drugs in vitro. By integrating computational modelling, biomimetic microfluidic, and advanced data analysis, this research aims to deliver innovative solutions to global health challenges related to myocardial infarction and stroke, which remain leading causes of global death and disability. The PhD student will be based at RMIT's city campus, leveraging advanced facilities such as the cleanroom and fluid dynamics laboratories, with periodic travel to Monash University's Clayton campus required for blood-based experimentation and further analysis.