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The Linking Early Neurodevelopment to Neural Circuit Outcomes RFA aims to bridge the gap in our understanding of whether and how developmental phenotypes caused by autism risk gene mutation lead to altered circuit formation and function. The objective of this RFA is to bridge this critical gap in understanding how developmental events impact later processes of circuit formation and function in ASD. SFARI strongly encourages proposals involving close collaboration between investigators from a range of backgrounds, such as developmental neurobiologists and circuit neuroscientists, in order to convincingly demonstrate causal links between disparate phenotypes in the chosen model(s). The program envisions bringing together scientists from a range of backgrounds to collaboratively conduct thorough characterizations of how early developmental events result in alterations to ASD-relevant neural circuitry in carefully chosen models.