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The PhRMA Foundation's Postdoctoral Fellowship in Translational Medicine supports individuals engaged in a multidisciplinary, collaborative research training program at an accredited U.S. university that will extend their credentials in translational medicine. The fellowship aims to bring scientific research and technological advancements from the laboratory to the clinic to enhance the prevention, diagnosis, and treatment of disease. This includes adapting hypothesis-driven basic research discoveries for application in humans and taking clinical knowledge back to the bench. Research areas include development of innovative diagnostic or therapeutic approaches, precision medicine, novel clinical endpoints, human-relevant experimental and computational approaches, translational pharmacokinetics and pharmacodynamics, and hypothesis-based validation using human data or human-derived systems. All proposals must clearly state a therapeutically relevant hypothesis and applicants are expected to work with clinical collaborators to identify unmet clinical needs.