Discover Funding Opportunities

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NIAAA/NIDA R25 program is to support educational activities that foster a better understanding of biomedical, behavioral, and clinical research on alcohol and other substance use disorders and their implications. This FOA supports creative educational activities with a primary focus on Outreach, specifically designed to engage practicing health care professionals in education about current and emerging knowledge derived from scientific research on the neurobiology, epidemiology, prevention, and/or treatment of alcohol and other substance use disorders and related health conditions, with the ultimate goal of improving care for individuals who use alcohol and other substances.

This funding opportunity announcement (FOA) from the National Institutes of Health encourages applications for institutional research career development (K12) programs that propose to support intensive supervised research training and career development experiences for clinician scientists (Scholars) leading to research independence in the area of substance use and substance use disorder research. The program is designed to develop the next generation of clinical researchers in addiction science through structured mentorship and career development support. The K12 mechanism provides funding to institutions to develop and implement comprehensive career development programs for early-stage clinical researchers. This award aims to enhance the pool of well-trained, independent clinical investigators focused on advancing substance use and substance use disorder research.

This funding opportunity announcement supports high priority research at the intersection of HIV and substance use. The program invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). Applications are required to have a detailed research plan, preliminary data, and a clear description of the nexus with substance use. The FOA is open to both individual researchers and research teams and includes all areas of research from basic science to clinical and implementation research. All studies must focus on NIH HIV/AIDS Research Priorities as outlined in NOT-OD-20-018: UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding.

The purpose of the NIDA Animal Genetics Program is to identify genetic, genomic, and molecular (epi)genetic variants that underlie phenotypes associated with addictive behaviors and/or vulnerability to distinct stages along the substance use disorders (SUD) trajectory. This includes examining initial/acute use, escalation of use, acquisition of tolerance, dependence, uncontrolled use, abstinence and relapse or recovery. Applications may examine behaviors associated with SUD such as impulsivity, novelty seeking, and delayed discounting, as well as comorbidities demonstrating genetic correlations with phenotypes and behaviors linked with SUD including anxiety, stress, poor maternal care, and social defeat. NIDA encourages applications that take genomics, multi-omics, and/or data-based approaches that integrate multi-level omics data, delineate gene networks, and/or uncover the function of known or newly discovered genetic or epigenetic variants. Other areas of interest include genomics analysis at the circuit level and the application of neuroscience to genomics studies. NIDA expects these studies to uncover novel mechanisms that contribute to various stages across the SUD trajectory and inform future studies about potential targets and therapeutic strategies for addiction.