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The NIH Pathway to Independence Award (K99/R00) program is designed to increase and maintain a strong cohort of new and talented, NIH-supported, independent investigators. This program facilitates a timely transition of outstanding postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program provides independent NIH research support during this transition in order to help awardees launch competitive, independent research careers. The K99/R00 mechanism specifically supports basic experimental studies with humans required, providing funding across multiple NIH institutes and centers. This funding opportunity is designed to bridge the critical gap between postdoctoral training and independent faculty positions, helping talented early-career investigators establish themselves as independent researchers.

The purpose of the NIH Independent Scientist Award (K02) is to foster the development of outstanding scientists and enable them to expand their potential to make significant contributions to their field of research. The K02 award provides three to five years of salary support and protected time for newly independent scientists who can demonstrate the need for a period of intensive research focus as a means of enhancing their research careers. This Parent Funding Opportunity Announcement is for basic science experimental studies involving humans, specifically prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should be submitted include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this R25 program is to support educational activities that foster a better understanding of biomedical, behavioral and clinical research and its implications. This funding opportunity announcement (FOA) will support creative educational activities with a primary focus on research experiences for high school or undergraduate students or science teachers during the summer academic break. The proposed program needs to fit within the mission of the participating NIH Institute or Center (IC) that the application is being submitted to and should not have a general STEM focus. This program aims to enhance research education and training in biomedical, behavioral, and clinical research areas aligned with NIH's mission.

The National Institutes of Health (NIH) notifies recipient organizations holding specific types of NIH grants that applications for change of recipient organization may be submitted to this NOFO. This assumes such a change is programmatically permitted for the particular grant. Applications for change of recipient organization are considered prior approval requests and will be routed for consideration directly to the Grants Management Specialist named in the current award. Although requests for change of recipient organization may be submitted through this NOFO, there is no guarantee that an award will be transferred to the new organization. All applicants are encouraged to discuss potential requests with the awarding IC before submission. This opportunity covers multiple NIH assistance listings including cancer research, infectious diseases, mental health, cardiovascular diseases, drug abuse research, and many other health-related research programs.

The purpose of this notice of funding opportunity (NOFO) is to provide salary support for exceptional Research Software Engineers (RSEs) that contribute their skills to the development and dissemination of biomedical, behavioral or health related software, tools, and algorithms as well as to the training of prospective users of these tools. This award supports RSEs working in various health-related domains including sleep disorders, minority health, diabetes, neurosciences, oral diseases, musculoskeletal research, genomics, child health, cardiovascular diseases, cancer biology, drug abuse research, vision research, mental health, aging research, complementary health, alcohol research, environmental health, blood diseases, and medical library assistance.